Towards personalized analysis and treatment using dynamic imaging, finite element modeling and musculoskeletal simulations
Monday, 18 May 2026, 10:00–11:00 in HG03.082
Nico Verdonschot1,2 & Dennis Janssen1
1. Orthopaedic Research Laboratory (ORL), Radboud university medical center, Nijmegen, The Netherlands
2. Laboratory of Biomechanical Engineering, University of Twente, Enschede, The Netherlands
Abstract
At the ORL of Radboudumc we develop methods to enhance the treatment of orthopedic patients. We utilize dynamic imaging techniques (CT and MRI) to better diagnose the underlying pathology. These images also allow us to create models of these individual patients. We focus on their musculoskeletal system and try to assess how muscles generate forces and thereby generate joint forces which need to be endured by the cartilage (in osteoarthritic patients), orthopedic implants (e.g. after total knee replacement) or other reconstruction such as a torn anterior cruciate ligament. To assess the internal forces on these structures we combine the musculoskeletal models with finite element models as they provide the opportunity to calculate compressive stresses on the cartilage, or whether an orthopedic implant might loosen. Hence, by combining these tools we have generated unique pipelines to further optimize treatment of orthopedic patients in a personalized manner.